ACTG Polyclonal Antibody from Bioassay Technology Laboratory

Actins are highly conserved proteins that are involved in various types of cell motility: and maintenance of the cytoskeleton. In vertebrates: three main groups of actin isoforms: alpha: beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton: and as mediators of internal cell motility. Actin: gamma 1: encoded by this gene: is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26: a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants