IFN-alpha/beta R2 PE-conjugated Antibody FAB1083P from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIFN-alpha/beta R2 PE-conjugated Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $389.00Supplier Page View Company Product Page
Catalog NumberFAB1083P
NCBI Gene AliasesIFNABR, IFNARB, IMD45, IFN-R, Ifnar-2, IFN-R-2, IFN-alpha-REC
TargetIFN-alpha/beta R2
IsotypeIgG
ReactivityMouse,Rat
Quantity100 Tests
ApplicationsFlow Cytometry,Immunocytochemistry
Conjugate/TagPhycoerythrin
HostGoat
NCBI Full Gene Nameinterferon alpha and beta receptor subunit 2, interferon (alpha and beta) receptor 2
ClonalityPolyclonal
FormatSupplied in a saline solution containing BSA and Sodium Azide
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse IFN-alpha/ß R2, Ser22-Ala239 (Lys160Asn), Accession # Q9D1R7
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageProtect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Specifications/Features

Available conjugates: Available conjugates: Phycoerythrin

Specificity: Detects mouse IFN-alpha/ß R2 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) IFN-gamma R2 and rmIL-20 R alpha is observed, 5% cross-reactivity with recombinant human (rh) IL-10 Rß, rmIFN-gamma RI, and rhIL-20 Rß is observed and less than 1% cross-reactivity with rhIFN¿ß R alpha is observed.

Sizes Available: 100 Tests

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Questions and Answers

Can this antibody be used for flow cytometry applications?

Yes, the IFN-alpha/beta R2 PE-conjugated Antibody has been shown to work in flow cytometry applications, allowing for the detection of mouse IFN-alpha/beta R2.

What species can I use this antibody with in my experiments?

This antibody is reactive with mouse and rat species, making it suitable for studies involving these organisms.

How specific is this antibody in detecting its target?

The antibody specifically detects mouse IFN-alpha/beta R2 in direct ELISAs and Western blots, with approximately 10% cross-reactivity with recombinant mouse IFN-gamma R2 and IL-20 R alpha, and lower cross-reactivity with other human and mouse interleukin receptors.

What is the recommended storage condition for this antibody?

The IFN-alpha/beta R2 PE-conjugated Antibody should be protected from light and stored at 2 to 8 °C. It should not be frozen and is stable for 12 months from the date of receipt.

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axisCell researchOctober 1, 2022Zhang HG, Wang B, Yang Y, Liu X, Wang J, Xin N, Li S, Miao Y, Wu Q, Guo T, et al.

(2) JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down SyndromeCell reportsNovember 17, 2020Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, et al.PE,Biolegend,Cat# 400112; RRID: AB_2847529 Goat polyclonal IgG anti-mouse IFNAR2 conjugated to PE,R&D Systems,Cat# FAB1083P; RRID: AB_10718996 Goat polyclonal IgG isotype control for IFNAR2 conjugated to PE,R&D Systems,Cat#

(3) Mycobacterium tuberculosis Inhibits Autocrine Type I IFN Signaling to Increase Intracellular SurvivalJournal of immunology (Baltimore, Md. : 1950)April 15, 2019Banks DA, Ahlbrand SE, Hughitt VK, Shah S, Mayer-Barber KD, Vogel SN, El-Sayed NM, Briken V.PE-conjugated mouse anti-IFNAR1 (Biolegend, 127311) or PE-conjugated goat anti-IFNAR2 (R&D Systems, FAB1083P) for 30 min on ice. PE-conjugated mouse IgG1 (Biolegend, 400111) and goat IgG1 (R&D Systems, IC108P)

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