CYP4A (E-6) Antibody sc-271983 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCYP4A (E-6) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-271983
ClonalityMonoclonal
ApplicationsWB, IP, IF, IHC(P), ELISA
Hostmouse
Quantity200 µg/ml
Conjugate/TagUnconjugated
CloneE-6
Reactivitymouse, rat
Antibody TypePrimary Antibodies
TargetCYP4A
FormatPurified
IsotypeIgG1
NCBI Full Gene Namecytochrome P450, family 4, subfamily a, polypeptide 14

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicityJournal of Biological ChemistryMay 15, 2025Elizabeth Twum, Malvin Ofosu-Boateng, Daniel O. Nnamani, Lidya H. Gebreyesus, Nour Yadak, Kusum K. Kharbanda, Frank J. Gonzalez, Maxwell A. Gyamfi,Santa Cruz,Sc-393583,1:1000 CYP2E1,Abcam,AB28146,1:1000 LFABP1,Santa Cruz,Sc-374537,1:200 CPT1α,Abcam,AB128568,1:1000 CYP4A14,Santa Cruz,Sc-271983,1:500 PPARƔ,Santa Cruz,Sc-7273,1:1000 CIDEC (FSP27),Abcam,AB198204,1:1000 EGR1,Cell Signaling,4153S,1:1000 BCL-XL,Cell Signaling

(2) Reducing Oxidative Stress-Mediated Alcoholic Liver Injury by Multiplexed RNAi of Cyp2e1, Cyp4a10, and Cyp4a14BiomedicinesJuly 6, 2024Qi Zhang, Shuang Wu, Qiubing Chen, Yahong Zhang, Cai Zhang, Runting Yin, Zhen Ouyang, Yuan Weito detect the protein expression of CYP2E1 (BML-CR3271, Enzo Biochem, New York, NY, USA) and CYP4A (sc-271983, Santa Cruz Biotechnology, Santa Cruz, CA, USA) in the liver microsomes. The protein expression of DPBS

(3) Overexpression of Human Soluble Epoxide Hydrolase Exacerbates Coronary Reactive Hyperemia Reduction in Angiotensin-II-Treated Mouse HeartsJournal of Cardiovascular PharmacologyJanuary 1, 2024Ahmad Hanif, Matthew L. Edin, Darryl C. Zeldin, Mohammed A. Nayeemwith non-fat dry milk, the nitrocellulose membranes were incubated with primary antibodies [CYP4A (sc-271983 from Santa Cruz Biotechnology), AT1R (sc-81671 from Santa Cruz Biotechnology]) and β-actin (Santa Cruz

(4) Overexpression of human soluble epoxide hydrolase exacerbates coronary reactive hyperemia reduction in Angiotensin-II treated mouse heartsJ Cardiovasc PharmacolJanuary 1, 2024Ahmad Hanif, Matthew L. Edin, Darryl C. Zeldin, Mohammed A. Nayeemwith non-fat dry milk, the nitrocellulose membranes were incubated with primary antibodies [CYP4A (sc-271983 from Santa Cruz Biotechnology), AT1R (sc-81671 from Santa Cruz Biotechnology]) and β-actin (Santa Cruz

(5) 20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathwayToxicology lettersJanuary 15, 2023Li B, Ma Y, Tan L, Ren H, Wu L, Su Q, Song J, Chen W, Gong P, Jin Y.

(6) Blockade of 20-hydroxyeicosatetraenoic acid receptor lowers blood pressure and alters vascular function in mice with smooth muscle-specific overexpression of CYP4A12-20-HETE synthaseJournal of hypertensionMarch 1, 2022Agostinucci K, Hutcheson R, Hossain S, Pascale JV, Villegas E, Zhang F, Adebesin AM, Falck JR, Gupte S, Garcia V, et al.containing 1% bovine serum albumin for 1 hour. Antibodies against CYP4A (1:1000 – Santa Cruz – cat#: sc-271983), ROCK1 (1:1000 – Sigma – cat#: HPA007567), Serine 1177 p-eNOS (1:100 – Cell Signaling Technology –

(7) The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver diseaseJCI insightAugust 23, 2021Yang Z, Smalling RV, Huang Y, Jiang Y, Kusumanchi P, Bogaert W, Wang L, Delker DA, Skill NJ, Han S, et al.SuperSignal West Pico Chemiluminescent Substrate (Thermo) was used according to the manufacturer’s protocol. The following Abs were used: CYP4A (sc-271983; Santa Cruz Biotechnology), ACTIN (sc-47778; Santa Cruz Biotechnology), and CYP2E1 (AB1252; Millipore). Metabolomic

(8) Feedback repression of PPARα signaling by Let-7 microRNACell reportsAugust 10, 2021Yagai T, Yan T, Luo Y, Takahashi S, Aibara D, Kim D, Brocker CN, Levi M, Motohashi H, Gonzalez FJ.REAGENT or RESOURCE,SOURCE,IDENTIFIER ,, Antibodies,, ,, Mouse monoclonal anti-CYP4A,Santa Cruz,Cat# sc-271983; RRID: AB_10715105 Mouse monoclonal anti-RNF8,Santa Cruz,Cat# sc-271462; RRID: AB_10648902 Mouse monoclonal

(9) 20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistanceProstaglandins & other lipid mediatorsFebruary 1, 2021Gilani A, Agostinucci K, Hossain S, Pascale JV, Garcia V, Adebesin AM, Falck JR, Schwartzman ML.technologies. Anti-phospho-IR-Tyr972 (I1783) and Ant-β-actin (A2228) antibody were from Sigma. Anti-CYP4A (sc-271983) was from Santa Cruz Biotechnology. This antibody recognizes all Cyp4a isoforms including Cyp4a10, Cyp4a12

(10) Proximal tubular-targeted overexpression of the Cyp4a12-20-HETE synthase promotes salt-sensitive hypertension in male miceAmerican journal of physiology. Regulatory, integrative and comparative physiologyJune 17, 2020Gilani A, Agostinucci K, Pascale JV, Hossain S, Kandhi S, Pandey V, Garcia V, Nasjletti A, Laniado Schwartzman M.

(11) Enhanced A(1) adenosine receptor-induced vascular contractions in mesenteric artery and aorta of in L-NAME mouse model of hypertensionEuropean journal of pharmacologyJanuary 5, 2019Yadav VR, Teng B, Mustafa SJ.acetyl choline (ACh), HET0016 and all other chemicals were purchased from Sigma-Aldrich. Antibodies for CYP4A (sc-271983), eNOS (sc-654) and actin (sc-47778) were purchased from Santa Cruz Biotechnology, Santa Cruz, CA. The

(12) Specific Inhibition of CYP4A Alleviates Myocardial Oxidative Stress and Apoptosis Induced by Advanced Glycation End-ProductsFrontiers in pharmacologyJanuary 1, 2019Wang R, Wang L, He J, Li S, Yang X, Sun P, Yuan Y, Peng J, Yan J, Du J, et al.

(13) High-fat diet-induced obesity and insulin resistance in CYP4a14(-/-) mice is mediated by 20-HETEAmerican journal of physiology. Regulatory, integrative and comparative physiologyNovember 1, 2018Gilani A, Pandey V, Garcia V, Agostinucci K, Singh SP, Schragenheim J, Bellner L, Falck JR, Paudyal MP, Capdevila JH, et al.(Danvers, MA). Anti-phospho-IR-Tyr-972 (I1783) and anti-␤-actin (A2228) antibody were from Sigma. Anti-CYP4A (sc-271983) was from Santa Cruz Biotechnology (Santa Cruz, CA). This antibody recognizes all Cyp4a isoforms, including

(14) Vascular endothelial over-expression of soluble epoxide hydrolase (Tie2-sEH) enhances adenosine A(1) receptor-dependent contraction in mouse mesenteric arteries: role of ATP-sensitive K(+) channelsMolecular and cellular biochemistryNovember 1, 2016Yadav VR, Hong KL, Zeldin DC, Nayeem MA.HET0016 and GO6976 were purchased from Sigma-Aldrich and Cayman chemicals, respectively. Antibodies CYP4A sc-271983, pERK sc-7383, ERK1 sc-93, sEH sc-166961, and actin sc-47778 were purchased from Santa Cruz Biotechnology, Santa

(15) Angiotensin II stimulation alters vasomotor response to adenosine in mouse mesenteric artery: role for A1 and A2B adenosine receptorsBritish journal of pharmacologyOctober 1, 2015Yadav VR, Nayeem MA, Tilley SL, Mustafa SJ.

(16) Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesityAmerican journal of physiology. Regulatory, integrative and comparative physiologyJuly 1, 2014Alfaradhi MZ, Fernandez-Twinn DS, Martin-Gronert MS, Musial B, Fowden A, Ozanne SE.4844" CuZnSOD,Goat,1:20000,"R&D Systems, no.AF3787" CYP4A14,Mouse,1:10000,"Santa Cruz Biotechnology, no. sc-271983" Cytochrome c,Mouse,1:1000,"Abcam, no. ab13575" eNOS,Rabbit,1:1000,"Cell Signaling, no. 9572" Fatty

(17) High salt diet exacerbates vascular contraction in the absence of adenosine A₂A receptorJournal of cardiovascular pharmacologyMay 1, 2014Pradhan I, Zeldin DC, Ledent C, Mustafa JS, Falck JR, Nayeem MA.

(18) Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγAmerican journal of physiology. Regulatory, integrative and comparative physiologyJanuary 1, 2013Nayeem MA, Pradhan I, Mustafa SJ, Morisseau C, Falck JR, Zeldin DC.

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CYP4A (E-6) Antibody

CYP4A (E-6) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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CYP4A (E-6) Antibody from Santa Cruz Biotechnology, Inc.

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