The Anti-ZSCAN22 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-ZSCAN22 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Kruppel-associated box zinc finger proteins (KRAB-ZFPs) make up the largest family of transcription factors in humans. KRAB-ZFPs are characterized by two domain structures: the N-terminal KRAB domain and a tandem array of C2H2 zinc fingers at the C-terminus. KRAB-ZFPs play a major role in the recognition and transcriptional silencing of transposable elements (TEs), consistent with an "arms race model" of KRAB-ZFP evolution against invading TEs. HKR2 is one of the zinc finger genes that are related to the GLI protooncogene (GLI) and are members of the Kruppel-related gene family. ZNF750 may be a new tumor suppressor in the tumorigenesis of esophageal squamous cell carcinoma (ESCC), and the inhibition of cell proliferation induced by ZNF750 may be partially through the regulation of KLF4 expression