The Anti-SMAGP Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-SMAGP Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
SMAGP (Small trans-Membrane And Glycosylated Protein) is a glycoprotein containing a transmembrane domain. SMAGP is strongly conserved during evolution. It is expressed by normal epithelia of various organs, the protein being notably localized to the lateral face of the plasma membrane of cohesive well-polarized epithelial cells. Besides, SMAGP contains binding domains for the protein 4.1 and the PDZ domain of MAGUK proteins. SMAGP might similarly be involved in a scaffolding protein complex, and therefore participate in the epithelium organization or subsequent functions. SMAGP localizes to the lateral face of the plasma membrane and is expressed in the cytoplasm after cell transformation. SMAGP plays a critical role in cell proliferation and tumorigenesis and could be a new therapeutic target in cervical cancer