MyBioSource.com's Rabbit Anti-DcR1/TRAILR3 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-DcR1/TRAILR3 Antibody was generated using TNFRSF10C as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, and Immunofluorescence.
Description
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a marker and a new therapeutic approach for PC