The Anti-ZNF280A Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-ZNF280A Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
ZNF280A, first identified through an integrative high-resolution whole-genome profiling in mantle cell lymphoma, is a member of the zinc-finger protein family, carrying a unique zinc-finger motif composed of two contiguous Cys2His2-type fingers. This Cys2His2-like fold group (C2H2) is by far the best-characterized class of zinc fingers, and it is extremely common in mammalian transcription factors. Although functioning in diverse biological roles by binding DNA or RNA and mediating protein-protein interactions, this class of zinc fingers is best known for its role in sequence-specific DNA-binding proteins via its typical tandem repeats, with two or more fingers comprising the DNA-binding domain of the protein that occupies the major groove of DNA