MyBioSource.com's Anti-GLYR1 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Glyoxylate reductase 1 homolog (GLYR1), also known as NP60 and N-PAC, was originally discovered as an oxidoreductase in plant research. This protein, which is encoded by a gene located on the 16p13.3 chromosome, contains three domains: PWWP, AT-hook and NAD binding regions. GLYR1 has a high mutation frequency in microsatellite instability colorectal cancer (MSI CRC) and is presumed to be a novel tumor suppressor. GLYR1 overexpression induces p21 transcriptional activation and increases caspase activity via a p53-independent pathway