MyBioSource.com's Anti-OPA3 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
The OPA3 protein is enriched in the inner mitochondrial membrane and has mitochondrial targeting signals. Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by urinary excretion of 3-methylglutaconic acid (MGC), optic atrophy and movement disorders, including ataxia and extrapyramidal dysfunction. At least four mutations in the OPA3 gene have been found to cause autosomal dominant optic atrophy and cataract