MyBioSource.com's Anti-MVP Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot. The Anti-MVP Antibody, Rabbit Polyclonal was generated using major vault protein, and MVP as the antigen and it reacts with Human.
Description
MVP (Major Vault Protein) is a Protein Coding gene. This gene encodes the major component of the vault complex. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT, and phosphoinositide 3-kinase/Akt signaling pathways. MVP is a ribonucleoprotein comprising a major part (>70%) of the vault particle. The human MVP is also known as lung resistance-related protein (LRP) represents the predominant component of vaults that may be involved in the defense against xenobiotics. The human MVP has been implicated in the development of drug resistance in cancer cells. MVP has been implicated in multidrug resistance, cellular transport, and malignant transformation. Overexpression of MVP has also been reported in brain tissue samples from the antiepileptic drug (AED)-resistant human focal epilepsies