The Anti-NKX1-2 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody to NKX1-2. This antibody recognizes Mouse antigen. The Anti-NKX1-2 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
NKX1-2 (NK1 Homeobox 2) is located on human chromosome 10q26.13. Structurally, the encoded NKX1-2 protein is reported to be 32381 Da in mass. The NKX1-2 (also known as NKX-1.1; C10orf121; bB238F13.2) gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.153 organisms have orthologs with human gene NKX1-2. NKX1-2 is related to sequence-specific DNA binding. An important paralog of this gene is NKX1-1. Nkx1-2 is a key regulator of mesendoderm formation. Nkx1-2 is a critical component of the gene regulatory network that operates downstream of Wnt/beta-catenin signaling to regulate the formation of mesendoderm