The Anti-SEMA6D Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-SEMA6D Antibody, Rabbit Polyclonal has been shown to work in the following applications: Western Blot.
Description
Semaphorins 6D (SEMA6D) is a member of the Semaphorin signaling family and acts both locally through cell-cell interactions and at a long distance through secretion of its ectodomain. SEMA6D may act both locally through cell-cell contacts and more distantly through diffusion of its cleaved ectodomain. The primary receptors of SEMA6D are PLXNA1 and PLXNA4, which belong to the Plexin receptor family. The extracellular domains of Plexins interact with Semaphorins, while the C-terminal tails of Plexins mediate intracellular signal transduction. Semaphorins 6D is abnormally expressed in many cancers. SEMA6D is widely upregulated in gastric cancer and esophageal cancer, and participates in the regulation of cancer progression