MyBioSource.com's Anti-PACSIN1 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Anti-PACSIN1 Antibody, Rabbit Polyclonal was generated using PACSIN1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
PACSIN1 is an important Tau binding partner in regulating microtubule dynamics and forming axonal plasticity.PACSIN1 interacts with Tau in axon. PACSIN1 blockade results in impaired axonal elongation and a higher number of primary axonal branches in mouse dorsal root ganglia neurons, which is induced by increasing the binding ability of Tau to microtubules. In PACSIN1-blocked dorsal root ganglia neurons, a greater amount of Tau is inclined to accumulate in the central domain of growth cones, and it promotes the stability of the microtubule network