The Rabbit Anti-Desmoglein 1/DSG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Desmoglein 1, and DSG1. This antibody recognizes Human antigen. The Rabbit Anti-Desmoglein 1/DSG1 Antibody has been shown to work in the following applications: Western Blot.
Description
Fogo selvagem (FS), the endemic form of pemphigus foliaceus (PF), is characterized by pathogenic anti-desmoglein 1 (DSG1) autoantibodies. The anti-DSG1 response in FS is antigen driven and that selection for mutant anti-DSG1 B cells begins well before the onset of disease. Dsg1, the prototype of the desmoglein family, is a major component of epidermal desmosomes and the antigenic target of antibodies found in the sera of patients with the blistering disease, pemphigus foliaceus