MyBioSource.com's Anti-NRF1 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed. The Anti-NRF1 Antibody, Rabbit Polyclonal was generated using NRF1, and nuclear respiratory factor 1 as the antigen and it reacts with Human.
Description
NRF1 (Nuclear Respiratory Factor 1) is a Protein Coding gene. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes. The encoded protein belongs to the NRF1/Ewg family. NRF1 serves as a transcription factor that activates the expression of a wide range of nuclear genes essential for mitochondrial biogenesis and function, including mitochondrial respiratory complex subunits, heme biosynthetic enzymes, and regulatory factors involved in the replication and transcription of mitochondrial DNA. NRF1 plays a crucial role in regulating the expression of a broad range of mitochondrial genes in the nucleus in response to cellular oxidative stress. The protein has also been associated with the regulation of neurite outgrowth