The Rabbit Anti-T Plastin/PLS3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to plastin 3, and PLS3. This antibody recognizes Human antigen. The Rabbit Anti-T Plastin/PLS3 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). PLS3 contains 2 actin-binding domains, 4 CH (calponin-homology) domains and 2 EF-hand domains. It is expressed in a variety of organs, including muscle, brain, uterus and esophagus