MyBioSource.com's Anti-OTX2 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-OTX2 Antibody, Rabbit Polyclonal was generated using OTX2 as the antigen and it reacts with Human.
Description
OTX2 is a member of a highly conserved family of bicoid-like homeodomain transcription factors responsible for the regulation of cerebellar development. Orthodenticle homeobox 2 (OTX2) controls essential, homeostatic retinal pigment epithelial (RPE) genes in the adult. Mutations in OTX2 are mostly identified in patients with anophthalmia/microphthalmia with variable severity. The OTX2 homeobox gene plays a crucial role in craniofacial morphogenesis during early embryo development. Otx2 knockout embryos fail to form a head. The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development