MyBioSource.com's Rabbit Anti-IL-6 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-IL-6 Antibody was generated using IL6, and Interleukin 6 as the antigen. It reacts with Rat. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA.
Description
Interleukin-6 (IL-6) is a multifunctional alpha-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity