MyBioSource.com's Anti-TBCC Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
Human Tubulin Binding Cofactor C (TBCC) is a post-chaperonin involved in the folding and assembly of alpha-and beta-tubulin monomers leading to the release of productive tubulin heterodimers ready to polymerize into microtubules. In this process, it collaborates with other cofactors (TBC's A, B, D, and E) and forms a supercomplex with TBCD, beta-tubulin, TBCE, and alpha-tubulin. TBCCD1 is an enigmatic member of the tubulin-binding cofactor C (TBCC) family of proteins required for mother-daughter centriole linkage in the green alga Chlamydomonas reinhardtii and nucleus-centrosome-Golgi linkage in mammalian cells. TBCC is essential for the proper folding of alpha-and beta-tubulins into microtubule polymerizable heterodimers. TBCC is identified as a target of miR-1251-5p to be negatively associated with cell cycle and autophagy