MyBioSource.com's Anti-SUPT5H Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
SUPT5H, a suppressor of Ty homolog-5 (SPT5), was identified as a novel tumor-specific hTERT promoter-binding protein and activator in colon cancer cells. The N terminus of SUPT5H is highly acidic, while the C terminus contains 7 mitogen-activated protein (MAP) kinase consensus sequences. SUPT5H is an evolutionarily conserved component of the DRB sensitivity-inducing factor complex that regulates RNA Polymerase II dependent mRNA processing and transcription elongation. SUPT5H may potentially be used as a novel tumor biomarker and/or cancer therapeutic target