MyBioSource.com's Anti-C3orf52 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
C3ORF52 (also called TTMP), located on chromosome 3q13.2, has a central transmembrane domain predicted to span the endoplasmic reticulum membrane. C3ORF52 gene contains 6 exons and span approximately 33 kb. C3ORF52 shares 68% amino acid identity with the mouse homolog. 3 alternatively spliced human isoforms have been reported. TPA-induced transmembrane protein (TTMP) is up-regulated following treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) in the pancreatic cancer cell line HPAF-II. The up-regulation by TPA is triggered at the promoter level. Loss-of-function variants in C3ORF52 result in localized autosomal recessive hypotrichosis