The Anti-TBX5 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody to TBX5. This antibody recognizes Mouse, and Rat antigen. The Anti-TBX5 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
The T-box gene family refers to a group of transcription factors that share a highly conserved, sequence-specific DNA-binding domain (T-box) containing around 180-amino acids. The TBX5 gene, a member of the T-box family, is associated with congenital heart disease, electrocardiographic parameters, and development of atrial fibrillation in the general population. TBX5 is a vital transcription factor involved in cardiac development in a dosage-dependent manner. Mutations in the TBX5 gene, encoding T-box transcription factor, are a major cause of Congenital heart diseases (CHDs)