MyBioSource.com's Anti-TWIST1 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Anti-TWIST1 Antibody, Rabbit Polyclonal was generated using TWIST1 as the antigen and it reacts with Mouse.
Description
Twist, short for twist family bHLH transcription factor 1, is a critical epithelial-mesenchymal transition (EMT)-inducing transcription factor that increases expression of Vimentin. TWIST1 (TW) is a bHLH transcription factor (TF) and master regulator of the EMT. TWIST1 is an important upstream mediator of mutant Htt-induced neuronal death and may in part operate through epigenetic mechanisms