The Anti-LRP10 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody to LRP10. This antibody recognizes Human antigen. The Anti-LRP10 Antibody, Rabbit Polyclonal has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. Human LRP10 cDNA encodes a 1905 amino acid type I membrane protein consisting of five functional domains characteristic of the LDLR gene family. It is widely expressed in the esophagus, colon, and other tissues. LRP10 plays a significant role in brain physiology other than lipoprotein metabolism. It is associated with a series of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease which share genetic risk factors and pathophysiological processes with amyotrophic lateral sclerosis (ALS)