MyBioSource.com's Rabbit Anti-Carbonic anhydrase II Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Carbonic anhydrase II Antibody was generated using CA2, and carbonic anhydrase 2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA.
Description
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase II is one of fourteen forms of human alpha carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1