The Anti-SLC3A1 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-SLC3A1 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, and Immunofluorescence.
Description
The uptake of cysteine mainly depends on heterodimeric amino acid transporters (HATs) present on the cytoplasma membrane, consisting a heavy chain SLC3 (solute carrier 3) and a light chain SLC7. The heavy chain SLC3 is essential for plasma membrane localization and the light chain stabilization. Two heavy chains, SLC3A1 and SLC3A2 have been identified. SLC3A2 interacts with most the light chain whereas SLC3A1 has been known to form a heterodimer only with SLC7A9, a family member of light chain. The solute carrier family 3, member 1 (SLC3A1) is the cysteine carrier and mutations and deletions of this gene are associated with cystinuria. SLC3A1 protein is mainly expressed in the apical plasma membrane in the epithelial cells of intestinal mucosa and the renal proximal tubule