The Anti-PPP2R2A Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-PPP2R2A Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Protein Phosphatase 2 Regulatory Subunit Balpha (PPP2R2A) is one of the regulatory subunits of the PP2A phosphatase complexes, and its upregulation promotes cancer cell survival and growth. PPP2R2A is a potent negative regulator of the ERK pathway activation and bladder cancer cell proliferation. PPP2R2A acts as a mediator of miR-21-induced oncogenic effects in bladder cancer. PPP2R2A represents a new miR-21 direct target and regulator of the ERK pathway and bladder cancer cell growth