The Anti-NUDT22 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-NUDT22 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Western Blot.
Description
Human NUDT22 belongs to the diverse NUDIX family of proteins. NUDT22 (Nudix Hydrolase 22) is located on human chromosome 11q13.1. NUDT22 is related to hydrolase activity. Human NUDT22 is an Mg2+-dependent UDP-glucose and UDP-galactose hydrolase, producing UMP and glucose 1-phosphate or galactose 1-phosphate. NUDT22 hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. The preferred substrate is UDP-glucose. The NUDIX domain of NUDT22 contains a modified NUDIX box identified using structural analysis and confirmed through functional analysis of mutants. Human NUDT22's distinct structure and function as a UDP-carbohydrate hydrolase establish a unique NUDIX protein subfamily