The Rabbit Anti-PIG3 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to TP53I3. This antibody recognizes Human antigen. The Rabbit Anti-PIG3 Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3