MyBioSource.com's Rabbit Anti-GSTP1/GST3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunoprecipitation, and Western Blot.
Description
Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. GSTP1 levels correlated negatively with tumor size and serum alpha-fetoprotein (AFP) in HCC patients, and higher GSTP1 levels were associated with longer overall survival (OS) and disease-free survival (DFS), the high GSTP1 levels provide a better prognosis through suppression of tumorigenesis in HCC. Dual-testing of HPV and the GSTP1 might prove an effective screening tool for cervical cancer. GSTP1 is highly expressed in various cancerous cells and pre-neoplastic legions, where it is involved in apoptotic resistance or metabolism of several anti-tumor chemotherapeutics. That GSTP1 is a marker of malignant and pre-malignant cells and is a promising target for visualization and drug development. GSTP1 is a largely investigated tissue biomarker in several malignancies such as prostate, breast, lung, and hepatocellular carcinoma with good performances, especially for purposes