The Rabbit Anti-PFN1/Profilin 1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PFN1, and profilin 1. This antibody recognizes Mouse, and Rat antigen. The Rabbit Anti-PFN1/Profilin 1 Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Mutations in the profilin 1 (PFN1) gene cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease caused by the loss of motor neurons leading to paralysis and eventually death. PFN1 is a small actin-binding protein that promotes formin-based actin polymerization and regulates numerous cellular functions