MyBioSource.com's Anti-SLC28A3 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
Of the three human members of the SLC28 family, CNT3 (also known as SLC28A3) is characterized by the broadest tissue distribution and substrate specificity. High levels of CNT3 have been found in the pancreas, bone marrow, and mammary gland; lower levels have been found in the intestine, lung, prostate, testis, and liver. CNT3 is a symporter that couples the transport of one nucleoside to the symport of two Na+ ions or one proton. CNT3 is an important mediator of drug response and resistance to anti-cancer nucleoside analogs. For example, elevated CNT3 expression levels in chronic lymphocytic leukemia (CLL) is associated with lower complete response rate to fludarabine therapy