The Anti-RAB1A Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody to RAB1A. This antibody recognizes Human antigen. The Anti-RAB1A Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Rab1A is a newly identified mTORC1 activator that mediates an alternative amino acid (AA) signaling branch to Rag GTPases. Rab1a is a member of the Rab family of small GTPases with a well-characterized function in the regulation of vesicle trafficking from the endoplasmic reticulum to the Golgi apparatus and within Golgi compartments. RAB1A acts as an oncogene in various cancers, and emerging evidence has verified that RAB1A is a mTORC1 activator in hepatocellular and colorectal cancer. RAB1A acts as an oncogene by regulating cellular proliferation, growth, invasion, and metastasis via activation of the mTORC1 pathway in triple-negative breast cancer. RAB1A is an important small molecule in the mechanistic target of the rapamycin signaling pathway, which is one of the downstream signaling pathways of the epidermal growth factor receptor family