The Anti-SLC16A4 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-SLC16A4 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and pyruvate, across cell membranes. They are known to play an important role in cell metabolism, such as aerobic glycolysis and pH homeostasis. Currently, 14 gene members named SLC16A1 to SLC16A14 have been identified to have the presence of two highly conserved sequence regions located in TM1 and TM5, respectively, by topology study. MCT1 through MCT4 (MCTs 1-4) are H(+ )-coupled monocarboxylate transporters, MCT8 and MCT10 transport thyroid hormone and aromatic amino acids. SLC16A family members play crucial roles in tumorigenesis and tumor progression