The Anti-XPNPEP1 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-XPNPEP1 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
XPNPEP1 (X-Prolyl Aminopeptidase 1, also known as APP1) is a Protein Coding gene. The XPNPEP1 gene, located on 10q25.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat, etc. This gene encodes the cytosolic form of a Metallo-Aminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in the degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Deficiency of aminopeptidase P1, a cytosolic proline-specific peptidase encoded by the Xpnpep1 gene, causes an inborn error of metabolism (IEM) characterized by peptiduria in humans. XPNPEP1 is widely expressed in the small intestine, duodenum, and other tissues. Diseases associated with XPNPEP1 include Biliary Atresia and Parkinson's Disease 4, Autosomal Dominant