The Rabbit Anti-TXNDC17 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to TXNDC17. This antibody recognizes Human antigen. The Rabbit Anti-TXNDC17 Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. TXNDC17 is a novel 14-kDa disulfide reductase of the TXN (thioredoxin) family. TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. Moreover, TXNDC17 plays an important role in Taxol resistance via enhancing autophagy in human colorectal cancer cells. And TXNDC17 may become a potential target of colorectal cancer therapeutics