The Rabbit Anti-Integrin alpha V beta 6 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITGAV. This antibody recognizes Human antigen. The Rabbit Anti-Integrin alpha V beta 6 Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion