The Anti-SYNGR1 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, and Non-Human Primate antigen. The Anti-SYNGR1 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Synaptogyrin 1 (SYNGR1) is a transmembrane protein of neurotransmitter-containing vesicle. Suggestive association between SYNGR1 intragenic polymorphisms and schizophrenia has been reported in the Indian population. Furthermore, some rare nucleotide changes with a potential pathogenic effect have been found in Indian and Chinese schizophrenia patients. SYNGR1 is considered as a positional candidate gene for schizophrenia because of its location at chromosome 22q13, a region linked to schizophrenia, and its reduced expression in the postmortem brain of patients with schizophrenia. Additionally, genetic studies also reported the association of SYNGR1 is with schizophrenia and bipolar disorder in southern India. Genetic variants in UBASH3A and SYNGR1 may modify individual susceptibility to Rheumatoid arthritis (RA) in the Han Chinese population