MyBioSource.com's Rabbit Anti-MST1 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-MST1 Antibody was generated using STK4 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA.
Description
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a biomarker and therapeutic target for inflammation-induced HCC