MyBioSource.com's Anti-SLC6A18 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
SLC6A18 (solute carrier family 6, member 18) acts as a specific transporter for neurotransmitters, amino acids, and osmolytes such as betaine, taurine, and creatine. SLC6A18 is a member of the SLC6 Na(+)-and Cl(-)-dependent neurotransmitter transporter family. The orphan transporter Slc6a18 (XT2) is highly expressed at the luminal membrane of kidney proximal tubules and displays approximately 50% identity with Slc6a19 (B(0)AT1), which is the main neutral amino acid transporter in both the kidney and small intestine. As yet, the amino acid transport function of XT2 has only been experimentally supported by the urinary glycine loss observed in xt2 null mice. Slc6a18 and Slc6a19 have different roles in the intestine, and that both of these contribute to establishing the efficient neutral amino acid absorption system in the tilapia