MyBioSource.com's Rabbit Anti-Profilin 2 Antibody is a Rabbit monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
Profilin 2, also known as PFN2, is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. Profilin 2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. Profilin 2 is thought to regulate actin polymerization in response to extracellular signals. It inhibits the formation of IP3 and DG by binding to PIP2