MyBioSource.com's Anti-XKR6 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
The X Kell blood group complex subunit-related family member 6 (XKR6) gene (also known as XRG6, hCG_1991046, FLJ31557, C8orf5, C8orf7, or C8orf21; GeneID: 286046; HGNC: 27806) is located on chromosome 8p23.1. The 8p23.1 deletion syndrome is a rare multisystem disorder with high penetrance and a variable phenotypic spectrum that includes congenital heart disease, intellectual disability, behavioral problems, microcephalia, and sometimes epilepsy. Some of the genes in this region, particularly XKR6, may be involved in the pathogenesis of absence seizures. Two single-nucleotide polymorphisms (SNPs), XKR6 rs7460469 and XKR6 rs4240671, were significantly associated with systemic lupus erythematosus (SLE) or childhood-onset SLE in European or Korean populations but not in the Chinese population (XKR6 rs4240671 SNP). The XKR6 rs7819412 A allele was correlated with increased serum TG levels in patients with coronary heart disease (CHD) and TC levels in patients with ischemic stroke (IS) and a high risk of CHD and IS