MyBioSource.com's Anti-TXNDC16 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Thioredoxin Domain Containing 16 (also known as TXNDC16, ERp90, KIAA1344) is a meningioma-associated Ag. TXNDC16 is an endoplasmic reticulum (ER)-associated glycoprotein that may be released in exosomes. The human ERp90 cDNA encodes a protein of 825 amino acids. The N-terminal 27 residues are predicted to constitute an ER signal sequence, whereas no obvious ER retrieval motif is present at the C-terminus. The mature ERp90 protein has a calculated molecular mass of 90.5 kDa. The ERp90 gene is located on chromosome 14q22.1, and is predicted to cover 121.91 kb of genomic DNA and contain 21 exons. The secreted serum protein TXNDC16 is bound in circulating immune complexes, which were found both in meningioma and healthy blood donor sera. TXNDC16 is also associated with diseases such as Short Syndrome