The Anti-ZCCHC9 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-ZCCHC9 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
ZCCHC9 is a type of CCHC type zinc-finger containing protein that was found to be expressed in some tissues including the brain and testicles in mice. The CCHC-type zinc finger motif has numerous biological activities (such as DNA binding and RNA binding) and can also mediate protein-protein interaction. ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. Protein ZCCHC9 contains four CCHC motifs and is highly conserved in humans, mice, and rats. Cytoplasmic ZCCHC9 could promote the proliferation and invasion of NSCLC through the JNK pathway and may be a promising cancer maker. ZCCHC9 suppresses the transcription activities of NF-kappa B and SRE and may play roles in the Mitogen-Activated Protein Kinase (MAPK) signaling transduction pathway