The Rabbit Anti-Enoyl-ACP Reductase Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Bacteria/Archaea antigen. The Rabbit Anti-Enoyl-ACP Reductase Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP reductase which catalyzes the final and rate-limiting step of bacterial FAS. The antibiotic diazaborine interferes with the activity by binding to the protein. FABI is a potential target for selective antibacterial action, because it shows low overall sequence homology with mammalian enzymes. Various compounds have been reported as inhibitors of bacterial FabI-inhibitory compounds