MyBioSource.com's Rabbit Anti-GCNF/NR6A1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot. The Rabbit Anti-GCNF/NR6A1 Antibody was generated using NR6A1 as the antigen and it reacts with Human.
Description
NR6A1/CT150, as an orphan receptor, is a novel member of the cancer-testis (CT) antigen family. Nuclear receptor subfamily 6, group A, member 1 (NR6A1) is involved in regulating embryonic stem cell differentiation, reproduction, neuronal differentiation. Down regulation of NR6A1 could reverse epithelial-to-mesenchymal transition (EMT) process in DU145 and PC3 cell lines, and the overexpression could enhance EMT process in 22RV1 cell line. NR6A1 played a prominent role in migration and invasion of PCa cells, and it is indicated that NR6A1 may act as a novel marker for biochemical recurrence after radical prostatectomy