The Rabbit Anti-ROR beta Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Rabbit Anti-ROR beta Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Retinoic acid-related Orphan Receptors (RORs) belong to the nuclear receptor superfamily and are comprised of three members ROR alpha (RORA), ROR beta (RORB) and ROR gamma (RORC). RORs modulate gene expression by binding as a monomer to ROR response elements (ROREs) in the promoters of target genes. All three ROR genes exhibit significant sequence similarities and each is known to have multiple isoforms. While RORA is expressed by multiple tissues including skeletal muscles, liver, purkinje cells, thymus, kidney and adipose tissue among others the expression of RORB is limited to the central nervous system, retina, and pineal gland. The expression pattern of RORC is similar to that of RORA except that it is highly expressed in the thymus