The Anti-SLC35A3 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-SLC35A3 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
The covalent attachment of sugars to growing glycan chains is heavily reliant on a specific family of solute transporters (SLC35), the nucleotide sugar transporters (NSTs) that connect the synthesis of activated sugars in the nucleus or cytosol, to glycosyltransferases that reside in the lumen of the endoplasmic reticulum (ER) and/or Golgi apparatus. The SLC35 family are highly conserved type III transmembrane proteins that are divided into 7 subfamilies (SLC35A-G). UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form heterologous complexes in the Golgi membrane. NGT occurs in close proximity to mannosyl (alpha-1, 6-)-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase (Mgat5)