The Anti-VSIG1 Antibody, Rabbit Polyclonal from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Anti-VSIG1 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
V-set and immunoglobulin domain containing 1 (VSIG1) is a newly discovered member of the immunoglobulin superfamily of proteins, expressed in normal stomach and testis; it is encoded by a gene located on human chromosome X and preferentially expressed in a variety of cancers in humans. VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in the stomach, testis, and certain gastric, esophageal, and ovarian cancers. VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach. VSIG1 possesses tumor-suppressive functions that are translated into the favorable prognosis of VSIG1-expressing gastric cancer (GC) patients. Mouse VSIG1 interacts with Sertoli cells by heterophilic adhesion via its first Ig-like domain