Description
Product Characteristics: RNF26 Antibody: RNF26 was identified as a member of a novel C3HC5 ring finger subfamily (1). RNF26 is ubiquitously expressed in human tissues but has been found to be upregulated in several cancer cell lines including HL-60, HeLa S3, and SW480, as well as 50 % of primary gastric cancers. While the substrates of RNF26 ubiquitination have not yet been identified, the upregulation of RNF26 in several types of cancer suggest that it may serve as a target for therapeutic treatment (1).
Target Information: The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008]